Biotechnological applications of recombinant single-domain antibody fragments

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Biotechnological applications of recombinant single-domain antibody fragments

BACKGROUND Single-domain antibody fragments possess structural features, such as a small dimension, an elevated stability, and the singularity of recognizing epitopes non-accessible for conventional antibodies that make them interesting for several research and biotechnological applications. RESULTS The discovery of the single-domain antibody's potentials has stimulated their use in an increa...

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Single-domain antibody fragments with high conformational stability.

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cloning and expression of recombinant camelid single-domain antibody in tobacco

antibodies provide a suitable tool in fundamental research and their high affinity and specificity make them invaluable for diagnostic and therapeutic applications. a promising alternative to conventional antibodies are the heavy chain antibodies (vhh) of camelidae having short length, high solubility and stability are preferred to other antibody derivatives. in this study, our goal was product...

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ژورنال

عنوان ژورنال: Microbial Cell Factories

سال: 2011

ISSN: 1475-2859

DOI: 10.1186/1475-2859-10-44